The aim of this paper is to analyze the Lienzo de Tlaxcala, a sixteenth-century document, taking into consideration the different publics to which it was targeted. One version of this document was sent to the Spanish crown, where it was inserted in the European courtesan tradition of wall decoration with gobelin tapestries exalting the monarchy military and religious victories. In this context, the Lienzo de Tlaxcala worked as a conquest tapestry. At the same time, if we take into account the visual structure of the document, the location of some of the key places in it, and the comparison with some 18th century texts, we can propose that the Lienzo was interpreted as a map by Mesoamerican readers. Hence, the Lienzo de Tlaxcala could be con...